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1

Doubly diastereoselective nucleophilic additions to a bicyclic β,γ-unsaturated ketone possessing a conformationally mobile double bond

Leo A. Paquette, Keith S. Learn, Jeffrey L. Romine

Journal:

Année:

1987

Langue:

english

Fichier:

PDF, 831 KB

english, 1987

2

Reductive displacement of allylic acetates by hydride transfer via catalytic activation by palladium(0) complexes

Robert O. Hutchins, Keith Learn, Robert P. Fulton

Journal:

Tetrahedron Letters

Année:

1980

Langue:

english

Fichier:

PDF, 260 KB

english, 1980

3

Construction of a kinase inhibitor library via parallel synthesis

Rabindranath Tripathy, Keith S Learn, Dandu R Reddy, Mohamed Iqbal, Jasbir Singh, John P Mallamo

Journal:

Tetrahedron Letters

Année:

2002

Langue:

english

Fichier:

PDF, 147 KB

english, 2002

4

AMINE BORANES AS SELECTIVE REDUCING AND HYDROBORATING AGENTS. A REVIEW

Hutchins, Robert O., Learn, Keith, Nazer, Behrooz, Pytlewski, David, Pelter, Andrew

Journal:

Organic Preparations and Procedures International

Année:

1984

Langue:

english

Fichier:

PDF, 1.12 MB

english, 1984

5

1,2,3-thiadiazoles. I. Synthesis of sodium (or potassium) 1,2,3-thiadiazole-4-thiolates via thiocarbazonate esters and N-acylthiohydrazonate esters

Ving J. Lee, William V. Curran, Thomas F. Fields, Keith Learn

Journal:

Journal of Heterocyclic Chemistry

Année:

1988

Fichier:

PDF, 1.37 MB

1988

6

Local replication of simian immunodeficiency virus in the breast milk compartment of chronically-infected, lactating rhesus monkeys

Sallie R Permar, Helen H Kang, Andrew B Wilks, Linh V Mach, Angela Carville, Keith G Mansfield, Gerald H Learn, Beatrice H Hahn, Norman L Letvin

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 273 KB

english, 2010

7

Design of 7-amino-6-chloro-3H-imidazo[4,5-b]pyridine scaffold from 5-chloro-2,4-diaminopyrimidine pharmacophore: identification of potent inhibitors of anaplastic lymphoma kinase

Learn, Keith S., Wagner, Jason C., Albom, Mark S., Angeles, Thelma S., Huang, Zeqi, Ghose, Arup K., Wan, Weihua, Cheng, Mangeng, Dorsey, Bruce D., Ott, Gregory R.

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 185 KB

english, 2012

8

The development of a novel series of (quinolin-2-ylmethoxy)phenyl-containing compounds as high-affinity leukotriene receptor antagonists. 3. Structural variation of the acidic side chain to give antagonists of enhanced potency

Galemmo, Robert A., Johnson, William H., Learn, Keith S., Lee, Thomas D. Y., Huang, Fu Chih, Campbell, Henry F., Youssefyeh, Raymond, O'Rourke, Susan V., Schuessler, Glenn

Journal:

Journal of Medicinal Chemistry

Année:

1990

Langue:

english

Fichier:

PDF, 1.85 MB

english, 1990

9

Aminoborohydrides as reducing agents. 1. Sodium (dimethylamino)- and (tert-butylamino)borohydrides as selective reducing agents

Hutchins, Robert O., Learn, Keith, El-Telbany, Farag, Stercho, Yurly P.

Journal:

Journal of Organic Chemistry

Année:

1984

Langue:

english

Fichier:

PDF, 766 KB

english, 1984

10

Synthesis and Facile One-pot Aldol/Elimination/Diels-Alder Reaction of ß-Keto-Z-Dienylamides as Cytochalasin C Intermediates 1

Palmer, James T., Learn, Keith S., Fuchs, P. L.

Journal:

Synthetic Communications

Année:

1986

Langue:

english

Fichier:

PDF, 504 KB

english, 1986

11

Molecular recognition during 1,2-addition of chiral vinyl organometallics to chiral .beta.,.gamma.-unsaturated ketones. Case studies of three 7,7-disubstituted 2-norbornenones. Part 5

Paquette, Leo A., Learn, Keith S., Romine, Jeffrey L., Lin, Ho Shen.

Journal:

Journal of the American Chemical Society

Année:

1988

Langue:

english

Fichier:

PDF, 2.15 MB

english, 1988

12

)-7-Methyl-7-Vinylbicyclo[3.2.0]Hept-2-En-6-One

Paquette, Leo A., Learn, Keith S., Romine, Jeffrey L.

Journal:

Synthetic Communications

Année:

1987

Langue:

english

Fichier:

PDF, 190 KB

english, 1987

13

.pi.-Facially controlled nucleophilic additions of chiral vinylorganometallics to chiral .beta.,.gamma.-unsaturated ketones. 1. Double diastereoselection studies involving 7,7-dimethoxy-5-norbornen-2-one

Paquette, Leo A., Learn, Keith S.

Journal:

Journal of the American Chemical Society

Année:

1986

Langue:

english

Fichier:

PDF, 416 KB

english, 1986

14

Regio- and stereoselective reductive replacement of allylic oxygen, sulfur, and selenium functional groups by hydride via catalytic activation by palladium(0) complexes

Hutchins, Robert O., Learn, Keith

Journal:

Journal of Organic Chemistry

Année:

1982

Langue:

english

Fichier:

PDF, 414 KB

english, 1982

15

Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene D4 receptor antagonists. 4. Addition of chromone moiety enhances leukotriene D4 receptor binding affinity

Huang, Fu Chih, Galemmo, Robert A., Poli, Gregory B., Learn, Keith S., Morrissette, Mathew M., Johnson, William H., Dankulich, William P., Campbell, Henry F., Carnathan, Gilbert W., Van Inwegen, Richa

Journal:

Journal of Medicinal Chemistry

Année:

1991

Langue:

english

Fichier:

PDF, 539 KB

english, 1991

16

[IEEE 2008 IEEE Radio and Wireless Symposium - Orlando, FL, USA (2008.01.22-2008.01.24)] 2008 IEEE Radio and Wireless Symposium - Interference multiple access wireless network demonstration enabled by real-time multiuser detection

Learned, Rachel, Hombs, Brandon, Lande, Mark, Tranquilli, John, Russo, Leonard, Farkas, Joseph, Niedzwiecki, Joshua, Eisenberg, Yiftach, Conner, Keith, Sherman, Matthew, Brothers, L. Reggie, Pierce, B

Année:

2008

Langue:

english

Fichier:

PDF, 428 KB

english, 2008

17

Double Diastereoselection Operative During π-Facially Selective Addition of Chiral 1-Cyclopentenyllithium Reagents to (7R∗)-7-Metwyl-7-Vinylbicyclo[3.2.0]Hept-2-EN-6-One

Paquette, Leo A., Learn, Keith S., Romine, Jeffrey L.

Journal:

Synthetic Communications

Année:

1987

Langue:

english

Fichier:

PDF, 189 KB

english, 1987

18

Laparoscopic Surgery for Crohn’s Disease: Reasons for Conversion

Schmidt, C. Max, Talamini, Mark A., Kaufman, Howard S., Lilliemoe, Keith D., Learn, Peter, Bayless, and Theodore

Journal:

Annals of Surgery

Année:

2001

Langue:

english

Fichier:

PDF, 59 KB

english, 2001

19

Discovery of Clinical Candidate CEP-37440, a Selective Inhibitor of Focal Adhesion Kinase (FAK) and Anaplastic Lymphoma Kinase (ALK)

Ott, Gregory R., Cheng, Mangeng, Learn, Keith S., Wagner, Jason, Gingrich, Diane E., Lisko, Joseph G., Curry, Matthew, Mesaros, Eugen F., Ghose, Arup K., Quail, Matthew R., Wan, Weihua, Lu, Lihui, Dob

Journal:

Journal of Medicinal Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 3.46 MB

english, 2016